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Immunocytochemical studies of aquaporin 4 in the skeletal muscle of mdx mouse

✍ Scribed by Jian Wu Liu; Yoshihiro Wakayama; Masahiko Inoue; Seiji Shibuya; Hiroko Kojima; Takahiro Jimi; Hiroaki Oniki

Book ID
119470242
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
644 KB
Volume
164
Category
Article
ISSN
0022-510X

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Duchenne muscular dystrophy is an X-linked devastating disease due to the lack of expression of a functional dystrophin. Unfortunately, the dystrophin-deficient mdx mouse model does not present clinical signs of dystrophy before the age of 18 months, and the role of dystrophin in fiber integrity is