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Synthesis of proteoglycans is augmented in dystrophic mdx mouse skeletal muscle

✍ Scribed by Soledad Cáceres; Claudia Cuellar; Juan Carlos Casar; Jorge Garrido; Liliana Schaefer; Hans Kresse; Enrique Brandan


Book ID
114494981
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
249 KB
Volume
79
Category
Article
ISSN
0171-9335

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✍ Jacques Bobet; Robert F. Mooney; Tessa Gordon 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB

It has recently been suggested, based on studies of tissue pathology, that the limb muscles of old mdx mice may be a good model for the muscular changes seen in human Duchenne muscular dystrophy. To test this hypothesis, we measured force and stiffness of soleus and extensor digitorum longus (EDL) m