Immunity and suppression in radiation- and radiation leukemia virus (RadLV)-induced leukemogenesis
β Scribed by Eitan Yefenof; Yaacob Ben-David
- Book ID
- 113238761
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 450 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0145-2126
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π SIMILAR VOLUMES
The radiation leukemia virus (RadLV) is a chronic leukemia retrovirus that induces thymic lymphomas in C57BU6 mice after a latency of 3 to 6 months. During the pre-leukemic (PL) period, the number of thymic macrophages gradually increased up to 100 fold. Of the cells in a RadLV-induced lymphoma, 0.3
## Abstract Adult C57BL/6 mice inoculated intrathymically (i.t.) with the highly leukemogenic variant of the radiation leukemia virus (AβRadLV) develop suppressor cells capable of specifically abrogating a potential antiβtumor cytotoxic response __in vitro__. Suppressor cells were generated directl
C57BL/6 (B6) mice inoculated with the highly leukemogenic variant of the radiation leukemia virus (A-RadLV) develop suppressor cells capable of abrogating potential anti-tumor immunity in vitro and in vivo. Inoculation of B6 animals with the low-leukemogenic D-RadLV variant does not result in suppre