Cellular immune response induced by the radiation leukemia virus (RadLV)
β Scribed by Alpha Peled
- Book ID
- 113237890
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- English
- Weight
- 876 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0145-2126
No coin nor oath required. For personal study only.
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## Abstract Adult C57BL/6 mice inoculated intrathymically (i.t.) with the highly leukemogenic variant of the radiation leukemia virus (AβRadLV) develop suppressor cells capable of specifically abrogating a potential antiβtumor cytotoxic response __in vitro__. Suppressor cells were generated directl
lntrathymic inoculation of radiation-leukemia virus (RadLV) into C57BL/6 mice induces a population of pre-leukemic (PL) T cells which progress into clonal, mature thymic lymphomas after a latency period of 3 to 5 months. In order to understand how PL cells are retained in the thymus for a prolonged