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Imidoester iodination of immunoglobulins to high specific activity

✍ Scribed by Georges P. Der-Balian

Publisher: Elsevier Science
Year: 1980
Tongue: English
Weight: 444 KB
Volume: 106
Category: Article
ISSN: 0003-2697
DOI: 10.1016/0003-2697(80)90541-2

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✦ Synopsis

Immunoglobulins were labeled via the di-iodinated derivative of methyl-para-hydroxybenzimidate (I). Radioactive iodine could be incorporated at high specific activities without alteration of the overall positive charge or significant inactivation of the antibody activity.

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