Imatinib for newly diagnosed chronic-phase chronic myeloid leukemia: results of a prospective study in Japan
β Scribed by Tadashi Nagai; Jin Takeuchi; Nobuaki Dobashi; Yuzuru Kanakura; Shuichi Taniguchi; Koji Ezaki; Chiaki Nakaseko; Akira Hiraoka; Masaya Okada; Yasushi Miyazaki; Toshiko Motoji; Masaaki Higashihara; Norifumi Tsukamoto; Hitoshi Kiyoi; Shinji Nakao; Katsuji Shinagawa; Ryuzo Ohno; Tomoki Naoe; Kazunori Ohnishi; Noriko Usui
- Book ID
- 107619071
- Publisher
- Carden Jennings Publishing
- Year
- 2010
- Tongue
- English
- Weight
- 284 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0925-5710
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π SIMILAR VOLUMES
## Abstract Imatinib at a dose of 400 mg daily is considered frontline treatment in chronic phase chronic myeloid leukemia (CPβCML). We conducted a systematic review and metaβanalysis of randomized controlled trials comparing frontline treatment with imatinib 400 mg daily versus higher doses (β₯600
## Abstract ## BACKGROUND Despite a lack of longβterm data, imatinib has become standard therapy for patients with newly diagnosed chronicβphase chronic myeloid leukemia (CML) who are not candidates for allogeneic stem cell transplantation. In the current study, the authors estimated the increment