Dasatinib versus Imatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia
β Scribed by Kantarjian, Hagop; Shah, Neil P.; Hochhaus, Andreas; Cortes, Jorge; Shah, Sandip; Ayala, Manuel; Moiraghi, Beatriz; Shen, Zhixiang; Mayer, Jiri; Pasquini, Ricardo
- Book ID
- 111694594
- Publisher
- Massachusetts Medical Society
- Year
- 2010
- Tongue
- English
- Weight
- 260 KB
- Volume
- 362
- Category
- Article
- ISSN
- 0096-6762
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π SIMILAR VOLUMES
## Abstract Imatinib at a dose of 400 mg daily is considered frontline treatment in chronic phase chronic myeloid leukemia (CPβCML). We conducted a systematic review and metaβanalysis of randomized controlled trials comparing frontline treatment with imatinib 400 mg daily versus higher doses (β₯600
## Abstract ## BACKGROUND Despite a lack of longβterm data, imatinib has become standard therapy for patients with newly diagnosed chronicβphase chronic myeloid leukemia (CML) who are not candidates for allogeneic stem cell transplantation. In the current study, the authors estimated the increment