Efficacy of imatinib dose escalation in patients with chronic myeloid leukemia in chronic phase
β Scribed by Hagop M. Kantarjian; Richard A. Larson; Francois Guilhot; Stephen G. O'Brien; Manisha Mone; Marc Rudoltz; Tillmann Krahnke; Jorge Cortes; Brian J. Druker; for the International Randomized Study of Interferon; STI571 (IRIS) Investigators
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 230 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Imatinib at a dose of 400 mg daily is considered frontline treatment in chronic phase chronic myeloid leukemia (CPβCML). We conducted a systematic review and metaβanalysis of randomized controlled trials comparing frontline treatment with imatinib 400 mg daily versus higher doses (β₯600
## Abstract ## BACKGROUND: The incidence, dynamics, and management of cytopenias were investigated in patients with chronic myeloid leukemia in chronic phase (CP CML) who received dasatinib therapy after imatinib failure. ## METHODS: Data were analyzed from 130 patients with CP CML who were trea
## Abstract ## BACKGROUND. The tolerability and efficacy of the combination of tipifarnib, an orally bioavailable nonpeptidomimetic farnesyl transferase inhibitor, and imatinib was investigated in patients with chronic myelogenous leukemia in chronic phase who had failed imatinib. ## METHODS. Tw