Illustrating conformational effects in acyclic systems
β Scribed by Sunderwirth, S. G.
- Book ID
- 125953493
- Publisher
- American Chemical Society
- Year
- 1964
- Tongue
- English
- Weight
- 277 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0021-9584
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π SIMILAR VOLUMES
Cyclic ketones from cyclobutanone to cyclohexadecanone were labelled with deuterium in the a-position. The deuterium isotope effect on the ''C NMR spectra was measured and in some cases was indicative of perturbation of conformational equilibrium. Similar effects were observed with acyclic ketones.
1n connection with another study,' we prepared some 1,2-dihalo-, 1,3-dihalo-, and 1,2,3trihalo-2,3-dimethylbutanes (I-III, X = Cl or Br). The nuclear magnetic resonance (nmr) spectra of these compounds reveal a surprising degree of conformational preference about C-C single bonds, such a preference,
## Abstract Conformations of aliphatic diastereoisomers with vicinal asymmetric centers (2,3βdisubstituted butanes and 5,6βdisubstituted __n__βdecanes) are discussed in terms of their ^13^C and, in some cases, ^15^N chemical shifts and spinβlattice relaxation times. Solvent and protonation effects