IL-12 up-regulates T-bet independently of IFN-γ in human CD4+ T cells
✍ Scribed by Emmi Ylikoski; Riikka Lund; Minna Kyläniemi; Sanna Filén; Maritta Kilpeläinen; Johannes Savolainen; Riitta Lahesmaa
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 280 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Fruit and vegetables have therapeutic potential as they dampen inflammation, have no known side‐effects and as whole foods have prospective additive and synergistic benefits. Th1 (IFN‐γ^+^CD4^+^)/Th2 (IL‐4^+^CD4^+^) T cells play a vital role in mediating inflammatory responses and may b
Phytohemagglutinin (PHA)-derived T lymphoblasts or T cell clones from patients genetically deficient in IL-12R g 1 (IL-12R g 1 -/-) or IFN-+ R1 (IFN-+ R1 -/-) produced two-to threefold reduced IFN-+ levels compared to the corresponding cells from healthy individuals after anti-CD3 and PMA stimulatio