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Correction: IL-12 up-regulates T-bet independently of IFN-γ in human CD4+ T cells

✍ Scribed by Emmi Ylikoski; Riikka Lund; Minna Kyläniemi; Sanna Filén; Maritta Kilpeläinen; Johannes Savolainen; Riitta Lahesmaa


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
80 KB
Volume
36
Category
Article
ISSN
0014-2980

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Phytohemagglutinin (PHA)-derived T lymphoblasts or T cell clones from patients genetically deficient in IL-12R g 1 (IL-12R g 1 -/-) or IFN-+ R1 (IFN-+ R1 -/-) produced two-to threefold reduced IFN-+ levels compared to the corresponding cells from healthy individuals after anti-CD3 and PMA stimulatio