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Identification of t(15;17) and a segmental duplication of chromosome 11q23 in a patient with acute myeloblastic leukemia M2

โœ Scribed by Shibo Li; Lijun Zhang; William F. Kern; Dario Andrade; Jean E. Forsberg; Francesca R. Bates; John J. Mulvihill


Book ID
114135394
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
167 KB
Volume
138
Category
Article
ISSN
0165-4608

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MLL is involved in a t(2;11)(p21;q23) in
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We describe a patient with acute myeloblastic leukemia (AML-M0) whose cells had a t(2;11)(p21;q23). Fluorescence in situ hybridization analysis with a probe for MLL showed that it was split, hybridizing to both the derivative 2 and 11 chromosomes. Nineteen other patients with 2p;11q translocations h