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New complex t(2;11;17)(p21;q23;q11), a variant form of t(2;11), associated with del(5)(q23q32) in myelodysplastic syndrome-derived acute myeloblastic leukemia

โœ Scribed by Katsuya Yamamoto; Kaoru Nagata; Yuriko Morita; Koichi Inagaki; Hiroyuki Hamaguchi

Book ID
114135374
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
244 KB
Volume
137
Category
Article
ISSN
0165-4608

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## Abstract We have identified a novel fusion partner of __MLL__, namely the mastermind like 2 (__MAML____2__ gene), in secondary acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) with inv(11)(q21q23). RTโ€PCR and sequencing revealed that exon 7 of __MLL__ was fused to exon 2 of __MAML