𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Identification of Hydrogen Bonds between Escherichia coli DNA Polymerase I (Klenow fragment) and the Minor Groove of DNA by Amino Acid Substitution of the Polymerase and Atomic Substitution of the DNA †

✍ Scribed by Spratt, Thomas E.


Book ID
121506221
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
68 KB
Volume
40
Category
Article
ISSN
0006-2960

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


A domain of the klenow fragment of Esche
✍ P. S. Freemont; Dr. D. L. Ollis; T. A. Steitz; C. M. Joyce 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 868 KB

The Klenow fragment of DNA polymerase I from Escherichia coli has two enzymatic activities: DNA polymerase and 3'-5' exonuclease. The crystal structure showed that the fragment is folded into two distinct domains. The smaller domain has a binding site for deoxynucleoside monophosphate and a divalent