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Identification of CYP2C9 as a Human Liver Microsomal Linoleic Acid Epoxygenase

โœ Scribed by Alison J. Draper; Bruce D. Hammock

Book ID
115568113
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
103 KB
Volume
376
Category
Article
ISSN
0003-9861

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โœ P. Bonnabry; T. Leemann; P. Dayer ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer ๐ŸŒ English โš– 447 KB

## Objective: The nature of the enzyme(s) catalysing the biotransformation of lornoxicam to one of its major metabolites, 5'-hydroxy-lornoxicam, has been investigated in human liver microsomes. the reaction kinetics were characterised, the affinity of lornoxicam for three major human drug metabolis