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The comparative interaction of human and bovine serum albumins with CYP2C9 in human liver microsomes

โœ Scribed by Qian Zhou; Satoshi Matsumoto; Li R. Ding; Nancy E. Fischer; Tadanobu Inaba

Book ID
116717484
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
332 KB
Volume
75
Category
Article
ISSN
0024-3205

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โœ P. Bonnabry; T. Leemann; P. Dayer ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer ๐ŸŒ English โš– 447 KB

## Objective: The nature of the enzyme(s) catalysing the biotransformation of lornoxicam to one of its major metabolites, 5'-hydroxy-lornoxicam, has been investigated in human liver microsomes. the reaction kinetics were characterised, the affinity of lornoxicam for three major human drug metabolis