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Identification of a new translocation that disrupts theRUNX1gene in a patient with de novo acute myeloid leukemia

✍ Scribed by Antonio Roberto Lucena-Araujo, Lorena Lobo de Figueiredo-Pontes, Fábio Morato de Oliveira, Maria de Lourdes Chauffaille, Roberto Passetto Falcao, Eduardo Magalhães Rego


Book ID
113093657
Publisher
Springer US
Year
2011
Tongue
English
Weight
261 KB
Volume
29
Category
Article
ISSN
1357-0560

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## Abstract We have shown that the __CBL__ gene at 11q23.3, telomeric to __MLL__, was fused to __MLL__ in an adult patient with de novo acute myeloid leukemia (FAB‐M1). Southern blot analysis indicated that the __MLL__ rearrangement was involved in the chromosomal abnormality. cDNA panhandle polyme