𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A new translocation that rearranges the AML1 gene in a patient with T-cell acute lymphoblastic leukemia

✍ Scribed by Fady M Mikhail; Kadreya A Serry; Nadia Hatem; Zeinab I Mourad; Hala M Farawela; Dalal M El Kaffash; Lionel Coignet; Giuseppina Nucifora


Book ID
114135288
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
249 KB
Volume
135
Category
Article
ISSN
0165-4608

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Complex MLL rearrangement in a patient w
✍ David S. Chervinsky; Sheila N. J. Sait; Norma J. Nowak; Thomas B. Shows; Peter D πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 735 KB

## Abstract __MLL__ (also known as __ALL‐1, HTRX__, or __HRX__) gene translocations are among the most common chromosomal abnormalities recognized in both B‐lineage acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). However, __MLL__ gene rearrangements are uncommon in T‐cell ALL.

A novel gene, FGA7, is fused to RUNX1/AM
✍ Fady M. Mikhail; Lionel Coignet; Nadia Hatem; Zeinab I. Mourad; Hala M. Farawela πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 517 KB

## Abstract __AML1__ is among the most frequent targets of chromosomal rearrangements in human leukemias. We report here the molecular analysis of a t(4;21)(q28;q22) that has disrupted __AML1__ in a patient with de novo T‐cell acute lymphoblastic leukemia. By using 3′‐RACE analysis, we show that th