✦ LIBER ✦

Identification and Structure of Small-Molecule Stabilizers of 14–3–3 Protein–Protein Interactions

✍ Scribed by Rolf Rose; Silke Erdmann; Stefanie Bovens; Alexander Wolf; Micheline Rose; Sven Hennig; Herbert Waldmann; Christian Ottmann

Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 844 KB
Volume: 49
Category: Article
ISSN: 0044-8249
DOI: 10.1002/anie.200907203

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Microarray-Assisted High-Throughput Iden

Microarray-Assisted High-Throughput Identification of a Cell-Permeable Small-Molecule Binder of 14-3-3 Proteins

✍ Hao Wu; Jingyan Ge; Shao Q. Yao 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 819 KB

Microarray-Assisted High-Throughput Iden

Microarray-Assisted High-Throughput Identification of a Cell-Permeable Small-Molecule Binder of 14-3-3 Proteins

✍ Hao Wu; Jingyan Ge; Shao Q. Yao 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 800 KB

Immunosuppressive Small Molecule Discove

Immunosuppressive Small Molecule Discovered by Structure-Based Virtual Screening for Inhibitors of Protein–Protein Interactions

✍ Tim Geppert; Stefanie Bauer; Dr. Jan A. Hiss; Elea Conrad; Michael Reutlinger; D 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 583 KB

Targeting Protein–Protein Interactions:

Targeting Protein–Protein Interactions: Suppression of Stat3 Dimerization with Rationally Designed Small-Molecule, Nonpeptidic SH2 Domain Binders

✍ Patrick T. Gunning; Matthew P. Glenn; Khandaker A. Z. Siddiquee; William P. Katt 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 286 KB

Applications of LC/MS in structure ident

Applications of LC/MS in structure identifications of small molecules and proteins in drug discovery

✍ Guodong Chen; Birendra N. Pramanik; Yan-Hui Liu; Urooj A. Mirza 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 263 KB

## Abstract With advancements in ionization methods and instrumentation, liquid chromatography/mass spectrometry (LC/MS) has become a powerful technology for the characterization of small molecules and proteins. This article will illustrate the role of LC/MS analysis in drug discovery process. Exam

ChemInform Abstract: Discovery of Small

ChemInform Abstract: Discovery of Small Molecule Inhibitors of Protein—Protein Interactions Using Combined Ligand and Target Score Normalization.

✍ Fergal P. Casey; Emilie Pihan; Denis C. Shields 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 15 KB 👁 1 views