A series of substituted 2-pyrrolidinones was evaluated for hypolipidemic activity a t 20 and 30 mg/kg/day in CF1 male mice. 4-Phenyl-5,5-dicarbethoxy-2-pyrrolidinone was the most potent compound a t 30 mg/kg/day, reducing serum triglyceride levels 52% after 14 days of dosing and serum cholesterol le
โฆ LIBER โฆ
Hypolipidemic Activity in Rodents of Phenobarbital and Related Derivatives
โ Scribed by I. H. Hall; M. A. Patrick; J. H. Maguire
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 634 KB
- Volume
- 323
- Category
- Article
- ISSN
- 0365-6233
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