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Hydrocortisone-dependent alterations of transcriptional activity in WI38 cells

โœ Scribed by J.M. Ryan; V.J. Cristofalo


Book ID
118877588
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
535 KB
Volume
122
Category
Article
ISSN
0014-4827

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Transcriptional activity of nuclei from
โœ Kiyoshi Nose; Hiroshi Okamoto ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 263 KB

## Abstract Transcriptional activity of nuclei from human diploid fibroblast (WIโ€38) cells at different passage levels was studied with endogenous RNA polymerase. The rate and extent of the RNA synthesis decreased when the nuclei were were prepared from senescent cells. The decreased activity of RN