Substantial clinical, epidemiologic, and experimental evidence has reinforced the role of high risk human papillomavirus (HPV) types in the development of cervical carcinoma. The authors investigated HPV in the uterine cervix squamous cell carcinomas and adenocarcinomas of Finnish patients. ## METH
Human papillomavirus type 16 is Detected in transitional cell carcinomas and squamotransitional cell carcinomas of the cervix and endometrium
โ Scribed by Ruth A. Lininger; Ignacio Wistuba; Adi Gazdar; Christopher Koenig; Fattaneh A. Tavassoli; Jorge Albores-Saavedra
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 399 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0008-543X
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โฆ Synopsis
The opinions and assertions contained herein are the private views of the authors and are not to be construed as official or as representing the views of the Department of the Army of the Department of Defense.
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## RESULTS. DO7, an anti-p53 monoclonal antibody, showed p53 overexpression in 35 carcinomas (53%). Consensus primer PCR showed HPV infection in 12 carcinomas
Human papillomaviruses (HPVs) have been recognized as an essential pathogenic factor in anogenital cancer. HPV DNA has also been found in a subgroup of head-and-neck squamous-cell carcinomas (HNSCCs), and a causative role of the virus in the development of these tumors has been suggested by the conc