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p53 mutations in relation to human papillomavirus type 16 infection in squamous cell carcinomas of the head and neck

โœ Scribed by Andrea G.M. Scholes; Triantafillos Liloglou; Peter J.F. Snijders; C. Anthony Hart; Andrew S. Jones; Julia A. Woolgar; E. David Vaughan; Jan M.M. Walboomers; John K. Field


Publisher
John Wiley and Sons
Year
1997
Tongue
French
Weight
66 KB
Volume
71
Category
Article
ISSN
0020-7136

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Loss of wild-type p53, either through deletion or mutation, has been demonstrated in most squamous cell carcinomas of the head and neck (HNSCC). Whether these mutant molecules contribute to tumor progression purely through loss of wild-type functions or by growth-promoting mechanisms, however, remai