## Background: The objective of the study was to evaluate the pathogenetic and prognostic value of p53 protein expression in squamous cell carcinoma of the vulva. ## Methods: The clinical data in charts of 167 patients with international federation of gynecology and obstetrics (figo) stages i-iii
p53 protein overexpression is common and independent of human papillomavirus infection in squamous cell carcinoma of the vulva
✍ Scribed by Marjolein J. Kagie; Gemma G. Kenter; Rob A. E. M. Tollenaar; Jo Hermans; J. Baptist Trimbos; Gert Jan Fleuren
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 85 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
✦ Synopsis
RESULTS.
DO7, an anti-p53 monoclonal antibody, showed p53 overexpression in 35 carcinomas (53%). Consensus primer PCR showed HPV infection in 12 carcinomas
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