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Human Pancreatic Carcinoma Cells Activate Maspin Expression Through Loss of Epigenetic Control

โœ Scribed by Fitzgerald, Matthew; Oshiro, Marc; Holtan, Nicholas; Krager, Kimberly; Cullen, Joseph J.; Futscher, Bernard W.; Domann, Frederick E.


Book ID
122247848
Publisher
Neoplasia Press
Year
2003
Tongue
English
Weight
556 KB
Volume
5
Category
Article
ISSN
1522-8002

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## Abstract Tumor cell expression of COXโ€2 has been implicated in the progression of murine and human lung cancer. Inhibition of COXโ€2 by nonsteroidal antiinflammatory drugs reduces the risk of cancer development in humans and suppresses tumor growth in animal models. However, the underlying mechan