Epigenetic silencing of maspin gene expr
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Frederick E. Domann; Judd C. Rice; Mary J.C. Hendrix; Bernard W. Futscher
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Article
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2000
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John Wiley and Sons
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French
โ 135 KB
๐ 2 views
Maspin is a tumor suppressor whose expression is lost in many advanced breast cancers. Maspin has been shown to inhibit cell motility, invasion and metastasis; however, its precise role in normal mammary epithelium remains to be elucidated. Although expression of maspin mRNA is low or absent in most