## Abstract __Epigenetics__ commonly refers to the developmental process by which cellular traits are established and inherited without a change in DNA sequence. These mechanisms of cellular memory also orchestrate gene expression in the adult brain and recent evidence suggests that the “epigenome”
How may stressful experiences contribute to the development of temporomandibular disorders?
✍ Scribed by Gustavo Hauber Gameiro; Annicele da Silva Andrade; Darcy Flávio Nouer; Maria Cecília Ferraz de Arruda Veiga
- Book ID
- 106236154
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 176 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1432-6981
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The nuclear transcription factor of activated T cells (NFAT) suggested to be a tumor suppressor. Here we report that two out of three NFATc3À/À and two in four NFATc3þ/À female mice developed aggressive mammary adenocarcinoma by 12.5 and 16 mo of age, respectively, with no occurrences in age-matched