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Homo-N-nucleosides: Incorporation into oligonucleotides and antiviral activity

✍ Scribed by N. Hossain; C. Hendrix; E. Lescrinier; A. Van Aerschot; R. Busson; E. De Clercq; P. Herdewijn


Book ID
104364596
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
222 KB
Volume
6
Category
Article
ISSN
0960-894X

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The synthesis of the aryl nucleoside analogue P2'-deoxy-D-ribofuranosyl-l'-N-pyrenylcarboxamide (4) is described. This compound can be converted into a phosphoranudite reagent and used in solid phase oligonucleotide synthesis.