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Synthesis of Modified Nucleosides for Incorporation of Formyletheno and Carboxyetheno Adducts of Adenine Nucleosides into Oligonucleotides

✍ Scribed by Koissi, Niangoran; Lönnberg, Harri

Book ID
126911297
Publisher
Taylor and Francis Group
Year
2007
Tongue
English
Weight
104 KB
Volume
26
Category
Article
ISSN
0732-8311

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The synthesis of the aryl nucleoside analogue P2'-deoxy-D-ribofuranosyl-l'-N-pyrenylcarboxamide (4) is described. This compound can be converted into a phosphoranudite reagent and used in solid phase oligonucleotide synthesis.