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hOGG1 Ser326Cys polymorphism and risk of lung cancer by histological type

✍ Scribed by Okasaka, Toshiki; Matsuo, Keitaro; Suzuki, Takeshi; Ito, Hidemi; Hosono, Satoyo; Kawase, Takakazu; Watanabe, Miki; Yatabe, Yasushi; Hida, Toyoaki; Mitsudomi, Tetsuya; Tanaka, Hideo; Yokoi, Kohei; Tajima, Kazuo


Book ID
120548247
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
341 KB
Volume
54
Category
Article
ISSN
1435-232X

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HOGG1 Ser326Cys polymorphism and modific
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## Abstract Oxidative stress is involved in many types of DNA damage, __e.g.,__ resulting in 8‐hydroxyguanine adducts. Since a human counterpart exists for the yeast gene __OGG1__ (__hOGG1__) encoding an enzyme that repairs 8‐hydroxyguanine, its polymorphism, Ser^326^Cys, might have potential as a