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hOGG1 Ser326Cys polymorphism and lung cancer susceptibility in the Turkish population

✍ Scribed by Esra T. Emerce; Bensu Karahalil; Bulent Kocer; Serdar Han; Necati Alkis; Ali Esat Karakaya

Book ID
119379577
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
83 KB
Volume
172
Category
Article
ISSN
0378-4274

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## Abstract The human oxoguanine glycosylase 1(hOGG1) gene encodes a DNA glycosylase that is involved in excision repair of 8‐OH‐dG (8‐hydroxy‐2‐deoxyguanine) from oxidatively‐damaged DNA. To determine whether hOGG1 plays a role in the risk for adenocarcinoma of the gallbladder, we tested the assoc

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Ser326Cys polymorphism in the hOGG1 gene, which is involved in the repair of 8-hydroxyguanine in oxidatively damaged DNA, has been identified and the variant genotype appears to be related to susceptibility to certain cancers. We investigated the association between Ser326Cys polymorphism and squamo