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History of the First Synthesis of 2-Deoxy-2-Fluoro-D-Glucose the Unlabeled Forerunner of 2-Deoxy-2-[18F]Fluoro-D-Glucose

✍ Scribed by Josef Pacák; Miloslav Černý

Book ID
117795632
Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
55 KB
Volume
4
Category
Article
ISSN
1536-1632

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Labeled 2-deoxy-D-glucose analogs. 18F-l
Labeled 2-deoxy-D-glucose analogs. 18F-labeled 2-deoxy-2-fluoro-D-glucose, 2-deoxy-2-fluoro-D-mannose and 14C-2-deoxy-2-fluoro-D-glucose
✍ T. Ido; C-N. Wan; V. Casella; J. S. Fowler; A. P. Wolf; M. Reivich; D. E. Kuhl 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 337 KB 👁 1 views

## Abstract A convenient method for the synthesis of ^18^F‐2‐deoxy‐2‐fluoro‐D‐glucose (4) and ^18^F‐2‐deoxy‐2‐fluoro‐D‐mannose (8) by the direct fluorination of 3,4,6‐tri‐0‐acetyl‐D‐glucal with ^18^F‐F~2~ is described. ^14^C‐2‐deoxy‐2‐fluoro‐D‐glucose has been synthesized from ^14^C‐3,4,6‐tri‐0‐ace