Highly stereospecific conversion of planar chirality of a cyclophane into axial chirality of binaphthyls
β Scribed by Tetsutaro Hattori; Nobuyuki Koike; Yoshikazu Okaishi; Sotaro Miyano
- Book ID
- 103408948
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 218 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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C-Centrochirality of 3,4-dihydro-2%-methoxy-2-methyl-2H-1,1%-binaphthalen-1-ol (R,R)-3e, which had been prepared by diastereoselective 1,2-addition of a 2-methoxy-1-naphthylytterbium reagent to 2-methyl-1-tetralone (R)-1b, was stereospecifically converted into axial chirality of 3,4-dihydro-2%-metho
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P-chiral phosphorothioate analogs of thymidine and adenosine nucleotides are transformed in high yield with retention of configuration by [180]chloral and [l80]styrene oxide into corresponding nucleoside [l\*O]phosphates. It has been shown in our recent reports that 18 0-labelled reagents such as di
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