Highly Efficient Molybdenum(II)-Catalyzed Intramolecular Allylic Alkylation of Arenes

✍ Scribed by Marco Bandini; Astrid Eichholzer; Peter Kotrusz; Achille Umani-Ronchi

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 193 KB
• Volume: 350
• Category: Article
• ISSN: 1615-4150
• DOI: 10.1002/adsc.200700607

✦ Synopsis

Abstract

The Friedel–Crafts‐type intramolecular allylic alkylation of simple arenes is performed in the presence of a catalytic amount of [Mo(II) (CO)~4~Br~2~]~2~ (2.5 mol%). The moisture‐tolerant protocol provided a mild and direct access to a large library of functionalized 4‐vinyl‐1,2,3,4‐tetrahydronaphthalenes in high yields.