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Total Synthesis of Enantiopure (+)-γ-Lycorane Using Highly Efficient Pd-Catalyzed Asymmetric Allylic Alkylation.

✍ Scribed by Bruno D. Chapsal; Iwao Ojima


Publisher
John Wiley and Sons
Year
2006
Weight
9 KB
Volume
37
Category
Article
ISSN
0931-7597

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Highly Diastereoselective Synthesis of 2
✍ Diego Savoia; Giuseppe Alvaro; Romano Di Fabio; Claudio Fiorelli; Andrea Gualand 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 238 KB 👁 1 views

## Abstract __C__~2~‐Symmetrical, enantiopure 2,6‐di[1‐(1‐aziridinyl)alkyl]pyridines (DIAZAPs) were prepared by a high‐yielding, three‐step sequence starting from 2,6‐pyridinedicarbaldehyde and (__S__)‐valinol or (__S__)‐phenylglycinol. The new compounds were tested as ligands in palladium‐catalyze