Highly Efficient Chiral-Pool Synthesis of (2S,4R)-4-Hydroxyornithine
β Scribed by Rudolph, Joachim; Hannig, Frithjof; Theis, Heidi; Wischnat, Ralf
- Book ID
- 115473521
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 44 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1523-7060
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π SIMILAR VOLUMES
A short synthesis of the nonproteinogenic amino acid, (2S,4R)-4-hydroxyornithine is described. Starting from racemic benzyl glycidol, the scaffold of the target compound was constructed in high enantio-and diastereoselectivity using Jacobsen's hydrolytic kinetic resolution (HKR) and regioselective o
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