Highlights from other journals - December 1998

Highlights from other journals - Decembe

Highlights from other journals - December 1999

📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 36 KB

## Synthesis of β-lactams The β-lactam ring is the key reactive functionality of all penicillin and cephalosporin antibiotics and has subsequently attracted attention as a target for combinatorial chemistry. However, solid-phase synthetic approaches to these molecules that might permit the synthes

Highlights from other journals - Decembe

Highlights from other journals - December 2000

📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 34 KB

## Highlights from other journals -December 2000 Small molecule binding at the Src SH2 domain A variety of proteins involved in signal transduction contain non-catalytic Src homology-2 (SH2) domains that function as mediators of intracellular protein-protein interactions. These SH2 domains (~100 a

Highlights from other journals

📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB

Autophagy, a tightly regulated homeostatic pro-survival mechanism, has also been implicated in pathogen recognition and clearance by macrophages as part of the innate immune response. In the May issue of EJI, Mitroulis et al. shed light into the role of autophagy in human neutrophil biology, associa

Highlights from other journals

📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB

Human genetic variation is associated with common traits and common diseases, and recent findings demonstrate the presence of population-specific copy number variations (CNVs), particularly those that involve genes of relevance for diseases and drug metabolism. Whilst representing a significant deve

Highlights from other journals

📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB

The methylotrophic yeast Pichia pastoris has become a platform for producing heterologous recombinant proteins of pharmaceutical importance, thanks to its ability to reproduce posttranslational modifications similar to those of higher eukaryotes. The groups of Sang Yup Lee and Diethard Mattanovich p

Highlights from other journals

📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB

A chronic immune response usually ends up producing collateral damage to the body as well as attacking the pathogen, but regulatory T cells (Treg) limit such damage. Acute infections can produce very vigorous immune reactions that are also capable of producing significant collateral damage, so does