✦ LIBER ✦

High-throughput screening technologies for drug glucuronidation profiling

✍ Scribed by Olga Trubetskoy; Moshe Finel; Vladimir Trubetskoy

Book ID: 111770864
Publisher: Pharmaceutical Press
Year: 2008
Tongue: English
Weight: 297 KB
Volume: 60
Category: Article
ISSN: 2042-7158
DOI: 10.1211/jpp.60.8.0012

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

New technologies for high-throughput scr

New technologies for high-throughput screening

✍ Jonathan J Burbaum; Nolan H Sigal 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 743 KB

To screen efficiently the millions of compounds that are synthesized using combinatorial and automated methods, dramatically improved assay technologies are currently needed. In 96-well microtiter plates, nonradioactive techniques (primarily fluorimetric) and cell-based functional methods have moved

New assay technologies for high-throughp

New assay technologies for high-throughput screening

✍ Lauren Silverman; Robert Campbell; James R Broach 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 607 KB

The use of high-throughput screening for early stage drug discovery imposes several constraints on the format of assays for therapeutic targets of interest. Homogeneous cell-free assays based on energy transfer, fluorescence polarization spectroscopy or fluorescence correlation spectroscopy provide

High throughput physicochemical profilin

High throughput physicochemical profiling for drug discovery

✍ Edward H. Kerns 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 440 KB

High throughput miniature drug-screening

High throughput miniature drug-screening platform using bioprinting technology

✍ Rodríguez-Dévora, Jorge I; Zhang, Bimeng; Reyna, Daniel; Shi, Zhi-dong; Xu, Tao 📂 Article 📅 2012 🏛 IOP Publishing 🌐 English ⚖ 783 KB

High-throughput screening: advances in a

High-throughput screening: advances in assay technologies

✍ G Sitta Sittampalam; Steven D Kahl; William P Janzen 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 999 KB

Both isotopic and nonisotopic assay methodologies are employed in high-throughput screening for drug discovery. Recent advances in cell-based and in vitro biochemical assays will be reviewed, with special emphasis on detection technologies amenable to automated 'mix and read' procedures in high-thro

Technological advances in high-throughpu

Technological advances in high-throughput screening

✍ Prabhavathi B Fernandes 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 906 KB

A variety of assay technologies continue to be developed for high-throughput screening. These include cell-based assays, surrogate systems using microbial cells such as yeast and bacterial two-hybrid and three-hybrid systems, and systems to measure nucleic acid-protein and receptor-ligand interactio