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High frequency of somatic missense mutation of BRCA2 in female breast cancer from Taiwan

โœ Scribed by Fang-Ming Chen; Ming-Feng Hou; Mei-Yin Chang; Jaw-Yuan Wang; Jan-Sing Hsieh; Fu Ou-yang; Tsung-Jen Huang; Shiu-Ru Lin


Book ID
116333421
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
160 KB
Volume
220
Category
Article
ISSN
0304-3835

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## Abstract Breast cancer occurs rarely in men and risk factors for the disease include germline mutations of the __BRCA2__ gene. High frequency of allelic loss at the __BRCA2__ locus has been reported in sporadic breast tumors, but somatic mutations of __BRCA2__ are very rare. Here we report the f