Germline mutations of BRCA2 were examined in 20 Japanese breast cancer families without BRCA1 mutations, including one demonstrating cancer development in a male. Three different mutations, resulting in truncation of the BRCA2 protein, were detected in 3 different families. They were 9474insA (exon
Frequency of BRCA1 and BRCA2 germline mutations in Japanese breast cancer families
β Scribed by Noriko Ikeda; Yasuo Miyoshi; Kohri Yoneda; Eiichi Shiba; Yoshizo Sekihara; Moritoshi Kinoshita; Shinzaburo Noguchi
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- French
- Weight
- 71 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0020-7136
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