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High-dose methotrexate clearance inhibited by benzimidazoles

Book ID
120850045
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2006
Weight
120 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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## Abstract Plasma methotrexate (MTX) concentrations were quantitated in 34 patients after 127 high‐dose (35–350 mg/kg) infusions with citrovorum factor rescue. Significant linear correlations have been obtained between methotrexate dosage and concentrations in plasma at 6 and 24 hours after the in