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Comparison of Hemodialysis versus Hemoperfusion in the Clearance of High-Dose Methotrexate in Pigs

✍ Scribed by Roberto Giardino; Milena Fini; Gianluca Giavaresi; Massimo Spighi; Stefano Faenza; Mario Leonardo Florio; Maurizio Orlandi; Sergio Stefoni

Book ID
115310787
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
389 KB
Volume
19
Category
Article
ISSN
0160-564X

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## Abstract Plasma methotrexate (MTX) concentrations were quantitated in 34 patients after 127 high‐dose (35–350 mg/kg) infusions with citrovorum factor rescue. Significant linear correlations have been obtained between methotrexate dosage and concentrations in plasma at 6 and 24 hours after the in