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Bayesian estimation and prediction of clearance in high-dose methotrexate infusions

✍ Scribed by Athanassios Iliadis; Maachou Bachir-Raho; René Bruno; Roger Favre

Book ID
112476316
Publisher
Springer
Year
1985
Tongue
English
Weight
864 KB
Volume
13
Category
Article
ISSN
1573-8744

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## Abstract Plasma methotrexate (MTX) concentrations were quantitated in 34 patients after 127 high‐dose (35–350 mg/kg) infusions with citrovorum factor rescue. Significant linear correlations have been obtained between methotrexate dosage and concentrations in plasma at 6 and 24 hours after the in