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High Accuracy of DNA Synthesis Catalyzed by the Complex of DNA Polymerases of the α Family in the Presence of Autonomous 3"→5" Exonucleases

✍ Scribed by I. V. Shevelev; N. V. Belyakova; T. P. Kravetskaya; E. A. Smirnova; V. M. Krutyakov

Book ID
110303359
Publisher
SP MAIK Nauka/Interperiodica
Year
2001
Tongue
English
Weight
28 KB
Volume
378
Category
Article
ISSN
1607-6729

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The 3′ → 5′ exonucleases of both DNA pol
The 3′ → 5′ exonucleases of both DNA polymerases δ and ε participate in correcting errors of DNA replication in Saccharomyces cerevisiae
✍ Morrison, Alan ;Sugino, Akio 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 832 KB

DNA polymerases II (epsilon) and III (delta) are the only nuclear DNA polymerases known to possess an intrinsic 3'-->5' exonuclease in Saccharomyces cerevisiae. We have investigated the spontaneous mutator phenotypes of DNA polymerase delta and epsilon 3'-->5' exonuclease-deficient mutants, pol3-01