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The Correcting Role of Autonomous 3" → 5" Exonucleases Contained in Mammalian Multienzyme DNA Polymerase Complexes

✍ Scribed by I. V. Shevelev; N. V. Belyakova; T. P. Kravetskaya; V. M. Krutyakov


Book ID
110410355
Publisher
SP MAIK Nauka/Interperiodica
Year
2002
Tongue
English
Weight
66 KB
Volume
36
Category
Article
ISSN
0026-8933

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The 3′ → 5′ exonucleases of both DNA pol
✍ Morrison, Alan ;Sugino, Akio 📂 Article 📅 1994 🏛 Springer 🌐 English ⚖ 832 KB

DNA polymerases II (epsilon) and III (delta) are the only nuclear DNA polymerases known to possess an intrinsic 3'-->5' exonuclease in Saccharomyces cerevisiae. We have investigated the spontaneous mutator phenotypes of DNA polymerase delta and epsilon 3'-->5' exonuclease-deficient mutants, pol3-01