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The proofreading 3′→5′ exonuclease activity of DNA polymerases: a kinetic barrier to translesion DNA synthesis

✍ Scribed by Vineeta Khare; Kristin A Eckert


Book ID
114070694
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
173 KB
Volume
510
Category
Article
ISSN
0027-5107

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The requirement for both DNA polymerase
✍ Sasakawa, Chihiro ;Uno, Yuko ;Yoshikawa, Masanosuke 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 615 KB

By assaying transposition of Tn5 from lambda b221 cI857 rex::Tn5 (Berg 1977) in polA-proficient and deficient cells, both the polymerase activity and 5' to 3' exonuclease activity of DNA polymerase I have been shown to be required for transposition. This requirement could not be observed in three ot