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Hereditary diffuse gastric cancer and E-cadherin: Description of the first germline mutation in an Italian family

✍ Scribed by F. Roviello; G. Corso; C. Pedrazzani; D. Marrelli; G. De Falco; A. Berardi; L. Garosi; G. Suriano; C. Vindigni; A. De Stefano; L. Leoncini; R. Seruca; E. Pinto


Book ID
116442838
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
658 KB
Volume
33
Category
Article
ISSN
0748-7983

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Screening E-cadherin in gastric cancer f
✍ Carla Oliveira; Maria Cristina Bordin; Nicola Grehan; David Huntsman; Gianpaolo πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 429 KB

The International Gastric Cancer Linkage Consortium (IGCLC) predicted that up to 25% of families fulfilling the criteria for hereditary diffuse gastric cancer (HDGC) would harbor CDH1 germline mutations. This was based on observations from the low number of diffuse gastric cancer families described