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Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families

✍ Scribed by Paul D.P. Pharoah; Parry Guilford; Carlos Caldas; The International Gastric Cancer Linkage Consortium

Book ID
119756408
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
566 KB
Volume
121
Category
Article
ISSN
0016-5085

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## Abstract Somatic mutations in the __E‐cadherin__ (__CDH1__) gene have frequently been reported in cases with diffuse gastric and lobular breast cancers. Recently, germline mutations have been identified in families with diffuse gastric cancers. In families with hereditary prostate cancer (HPC),