Heck reaction on solid support: synthesis of indole analogs
โ Scribed by Weiya Yun; Raju Mohan
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 193 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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๐ SIMILAR VOLUMES
Solid phase intramolecularHeck couplingallows the syothesisof 2-oxindoles. Additional diversityis introducedinfo the moleculeby reductiveatkylationprior to the Heck cyclisationarrdatso by conjugateadditionof a varietyof nucleophilesontothe cyctisedproductprior to cleavage. 01997 Elsevier ScienceLtd.
Golgi a-mannosidase II and lysosomal mannosidase are examples of biologically important a-mannosidases that are difficult to purify. Swainsonine is an effective inhibitor of these a-mannosidases. In this report, analogs of swainsonine bearing an aminoalkyl group at C3 or C6 are synthesized and coupl
Representative members from five different families of supported phosphine and phosphinite ligands have been prepared from common templates-polymer-bound aminoalcohols. These include b-aminophosphines, N,b-diphosphinoamines, a,b-diphosphinoamines, b-aminophosphinites and N-phosphino-b-aminophosphini