HBV genotypes prevalence, precore and basal core mutants in Morocco
β Scribed by Warda Baha; My Mustapha Ennaji; Fatiha Lazar; Marouane Melloul; Elmostafa El Fahime; Abdelouahad El Malki; Abdelouaheb Bennani
- Book ID
- 113798188
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 315 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1567-1348
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Hepatitis B virus (HBV) is characterized by genetic heterogeneity, including genotypes and mutations. Eight genotypes (A-H) have been identified throughout the world with a characteristic geographical distribution. Previous studies also suggest that the viral genotypes may correlate with differences
## Abstract One hundred fortyβtwo precore/core sequences were obtained from Gambian chronic hepatitis B virus (HBV) carriers and the predominant variants defined. The two point mutations, from A to T and G to A at nt positions 1762 and 1764 in the basic core promoter region, were found in only 7/99